Anastrozol 1 mg
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- Anastrozole 1 mg
- Brand: Magnus Pharmaceuticals
- Content: 30 tablets | 1 mg per tablet
- Manufactured in: Europe
Product Overview
Anastrozole 1 mg is a third-generation non-steroidal aromatase inhibitor (AI) designed to suppress peripheral estrogen synthesis via competitive inhibition of the CYP19 enzyme. Widely used in endocrine and oncology research, it allows for precise estrogen-reduction modeling, testosterone-to-estradiol (T:E) modulation, and post-cycle therapy simulations.
Its long half-life (~46–50 hours) supports once-daily dosing, and the film-coated tablets offer logistical advantages over injectables in hormone-regulation studies. With high selectivity and oral bioavailability, anastrozole is a key tool in studies of male hypogonadism, fertility, and body recomposition protocols.
Key Research Highlights
- Selective aromatase blockade: Inhibits CYP19 to suppress peripheral estrogen by 80% in vivo [DrugBank, NCBI]
- Extended half-life: Elimination t 46–50 hours supports consistent once-daily sampling [PubChem, Wikipedia]
- T:E ratio modulation:1 mg/day improved testosterone-to-estradiol ratios and semen metrics in male trials [PMC]
- Body recomposition support: Reduced systemic estrogen helps prevent gynecomastia and sustain lean-mass retention [Verywell Health]
- Room-temperature stability: Film-coated tablets store safely 25°C — no cold-chain required [Mayo Clinic]
Suggested Laboratory Applications
Aromatase inhibition and estrogen-suppression studies
Post-cycle therapy and hormonal recovery research
T:E ratio modulation in hypogonadal or fertility trials
Anti-estrogen support in anabolic-steroid modeling
Oncology research in estrogen-dependent tumors
Technical Specifications
| Field | Data |
|---|---|
| Chemical Name | Anastrozole |
| Chemical Formula | C<sub>17</sub>H<sub>19</sub>N<sub>5</sub> |
| Synonyms | Arimidex, ICI D1033, CP-65787, ,,-Tris(1H-1,2,4-triazol-1-yl-m-tolyloxy)-m-xylene |
| Molecular Weight | 293.37 g/mol |
| CAS Number | 120511-73-1 |
| Half-life | 46–50 hours |
Detection Window
Medium-to-long (varies with dose and sampling)
Documented Benefits
estrogen >80%, T:E ratio, recurrence of ER+ breast cancer
Main Risks
Arthralgia, hot-flushes, lipid shifts, bone-density reduction
Total Active Compound
30 mg per carton (1 mg 30 tablets)
Shelf-life
36 months (manufacturer specification)
PubChem-Supported Research Insights
Suppresses peripheral estrogen synthesis by over 80%
Increases T: E ratio in hypogonadal males and fertility models
Demonstrated efficacy in reducing recurrence of estrogen-dependent cancers
Supports lean tissue retention and gynecomastia control
Extended half-life allows single daily dosing for consistent hormonal regulation
Documented Research Side Effects
Joint pain, bone mineral density reduction, hot-flushes
Altered lipid profiles ( HDL, LDL) in chronic use
Cardiovascular strain risk with long-term administration
Insomnia and mood shifts in estrogen-sensitive models
Handling & Compliance
For Research Use Only — Not for human or veterinary useStore at 15–25°C, protect from moisture and lightPurchase confirms qualified researcher statusListed on WADA Prohibited List S4 — any exposure may result in a positive anti-doping test
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Package:30 tablets | 1 mg per tablet
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CAS Number:120511-73-1
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Molecular formula:C<sub>17</sub>H<sub>19</sub>N<sub>5</sub>
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Country of manufacture:Europe
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Half-life:46–50 hours