Methandienone Dianabol 10 mg

Methandienone (Dianabol) 10 mg — La Pharma

• Brand: La Pharma
• Category: Oral AAS Research Compound
• Content: 100 tablets 10 mg (1,000 mg total)
• Manufactured in: Thailand

Product Overview

Methandienone (methandrostenolone) 10 mg is a classic 17--alkylated anabolic-androgenic steroid (AAS)

developed for oral activity and widely used in laboratory settings for androgen-receptor (AR) signaling research,

protein synthesis studies, nitrogen-balance modeling, and steroid metabolism analysis. Its ability to aromatize to

17--methylestradiol provides a unique intersection of androgenic and estrogenic pathways, making it

scientifically valuable in multi-hormonal anabolic research.

Dianabol originated from mid-20th-century pharmaceutical development and has since become one of the most extensively

studied oral anabolic agents. Its well-documented pharmacology and metabolic behavior make it ideal for both analytical

method development and comparative AAS research.

Key Research Highlights

Potent AR agonist:

Methandienone binds to the androgen receptor, up-regulating anabolic gene transcription, protein synthesis, and nitrogen retention.

Aromatization to methylestradiol:

Its estrogenic conversion (unique among some oral AAS) allows study of water balance, estrogenic activity, and

endocrine cross-interactions.

Oral bioavailability:

17--methylation slows hepatic deactivation, enabling stable oral dosing in in-vitro and method-development research.

Historical data-rich compound:

Robust literature exists on lean-mass changes, metabolic alterations, hepatotoxic endpoints, and endocrine disruption.

Suggested Laboratory Applications

• Androgen receptor signaling and anabolic transcription studies
• Protein synthesis & nitrogen retention assays
• Comparative metabolism of aromatizable vs. non-aromatizable steroids
• Hepatotoxicity and metabolism studies on 17--alkylated steroids
• Estrogenic pathway modeling via aromatization products

Technical Specifications

Research Notes

Orally active AAS; increases lean mass & strength in controlled studies; carries hepatotoxic risk;

aromatizable to methylestradiol; WADA S1 prohibited.

Dosage Form & Pack

Oral tablets, 10 mg 100 tablets (1,000 mg total)

Shelf Life

36 months (store cool, dry, and protected from light)

Country of Manufacture

Thailand (La Pharma)

PubChem-Supported Research Insights

• Strong AR-binding and transcriptional upregulation
• Aromatization yields estrogenic metabolites relevant in water balance and gynecomastia models
• 17--alkylation increases hepatotoxicity in metabolic studies
• Supports comparative studies on oral steroid metabolism
• Widely used in anti-doping detection research due to characteristic metabolites

Documented Research Side Effects

• Hepatotoxicity, including cholestasis and transaminase elevation
• Dyslipidemia ( HDL / LDL) and hypertension markers
• Endocrine suppression and HPTA downregulation
• Estrogenic effects via aromatization (fluid retention, gynecomastia)
• Androgenic effects: acne, alopecia, sebaceous activity changes
• Reported behavioral effects in some models (aggression, mood shifts)

Handling & Compliance

For Research Use Only — analytical/in-vitro reference compound; not intended for human or veterinary use.

Methandienone is prohibited under WADA S1 and regulated as an AAS in many jurisdictions.

Appropriate chemical-safety procedures, secure storage, and regulatory compliance are required.