Methandrostenolone Danabol DS 10 mg

• Brand: DS
• Category: Oral AAS Research Compound
• Content: 500 tablets | 10 mg per tablet (5,000 mg total)
• Manufactured in: Thailand

Product Overview

Methandrostenolone 10 mg, commonly known as Danabol DS or “D-Bol,” is one of the earliest and most

extensively studied synthetic anabolic-androgenic steroids (AAS). As a structurally modified testosterone derivative,

it serves as a robust model compound for exploring anabolic pathways, nitrogen retention, metabolic regulation,

and hepatic processing of 17--alkylated oral steroids.

Originally introduced in the 1950s by CIBA under the brand Dianabol, methandrostenolone has a long research history

with well-established pharmacodynamic and toxicological profiles. The Danabol DS formulation offers reliable

oral bioavailability suitable for controlled-dose in-vitro and pre-clinical models.

Key Research Highlights

Protein synthesis & nitrogen retention:

Stimulates AR-mediated transcription and anabolic gene expression, enhancing muscle-cell protein synthesis.

Muscle hypertrophy modeling:

Used in research to evaluate fat-free mass gain, potassium balance, and anabolic-to-catabolic shifts.

Hepatic metabolism studies:

As a 17--alkylated steroid, it is integral to research on liver enzyme induction, cholestasis, and hepatocellular stress.

Comparative AAS research:

Reference standard in studies comparing potency, toxicity, and metabolic profiles of oral anabolic steroids.

Suggested Laboratory Applications

• Androgen receptor–mediated transcription and anabolic signaling
• Protein synthesis & nitrogen balance modeling
• Muscle hypertrophy and metabolic performance studies
• Liver-toxicity screening for 17--alkylated compounds
• Endocrine disruption research (HPG-axis suppression models)

Technical Specifications

PubChem-Supported Research Insights

• Binds AR with strong anabolic transcriptional output
• Promotes nitrogen retention and protein synthesis in metabolic studies
• 17--alkylated design increases both oral stability and hepatic strain
• Used broadly in pharmacology as a reference standard for anabolic potency
• Linked to lipid imbalance and hormonal feedback suppression in chronic models

Documented Research Side Effects

• Cholestatic liver injury, peliosis, adenomas/tumors (dose & duration dependent)
• Cardiovascular stress: HDL, LDL, potential hypertrophic markers
• Endocrine/HPTA suppression and hormonal imbalance
• Oxidative stress and altered gene expression in chronic models

Handling & Compliance

For Research Use Only — Not for human or veterinary consumption.

Store sealed in a cool, dry place away from light.

Handle under controlled research-chemical protocols, with secure storage and documentation.

Listed under controlled substances and WADA S1 anabolic agents.

Purchase and handling require qualified researcher compliance with all regulations.