Primobolan 25 mg

• Primobolan 25 mg
• Brand: Magnus Pharmaceuticals
• Content: 100 tablets | 25 mg per tablet
• Manufactured in: Europe

Product Overview

Primobolan 25 mg offers researchers an oral DHT-derived anabolic compound with exceptionally low androgenic and hepatic burden. Known scientifically as methenolone acetate, it is widely used in lean-mass preservation, catabolic-state models, and nitrogen-balance studies.

The acetate ester gives Primobolan a short oral half-life (~3–5 hours), requiring twice-daily dosing for stable plasma levels. Its minimal aromatisation, mild androgenicity, and long detection window (>10 days via LC-MS/MS) make it a key substance in cutting-phase protocols and anti-doping method development.

Key Research Highlights

Mild androgenic profile: In vitro studies show myotrophic potency exceeding testosterone, yet lower androgenic signalingShort half-life (oral): 3–5 hours; plasma levels best sustained by 2 daily dosesLiver safety: Absence of 17--methyl group significantly reduces hepatotoxic riskMinimal aromatisation: Estrogen conversion is virtually absent, reducing gynecomastia riskNitrogen retention: Clinical data confirms reduced urinary nitrogen loss in muscle-wasting statesAnti-doping classification: Long-term urinary metabolites allow detection >10 days post-exposure (WADA S1 listed)

Suggested Laboratory Applications

Lean-mass preservation in cutting-phase or post-illness models

Separation of androgenic and estrogenic pathways in body-recomp studies

Anti-doping detection trials with long half-life steroids

Muscle-wasting and catabolic stress research

Technical Specifications

Detection Window

>10 days (long-term metabolite)

Documented Benefits

Lean-tissue preservation, minimal water gain, low androgenic impact

Main Risks

HDL, testosterone suppression, rare cholestasis

Total Active Compound

2,500 mg per box (25 mg 100 tablets)

Storage / Shelf-life

Store 25 °C · 36 months (manufacturer specification)

PubChem-Supported Research Insights

Effective for nitrogen-balance support and lean-tissue preservation

Minimal hepatic stress compared to alkylated orals

Near-zero aromatisation supports estrogen-sensitive models

Ideal for testing long-range anti-doping detection protocols

Documented Research Side Effects

Reversible HDL suppression and mild HPG-axis inhibition

Rare reports of cholestasis in long-term exposure

Testosterone suppression in male models

Long-term metabolite excretion (WADA-positive)

Handling & Compliance

For Research Use Only — Not for human or veterinary useStore at 15–25°C, protect from light and moistureFollow SDS guidelines for safe handlingPurchase confirms qualified researcher status