Salbutamol 4 mg Tablets

Salbutamol 4 mg Tablets — Swiss Remedies

• Brand: Swiss Remedies
• Category: 2-Adrenergic Research Compound
• Content: 100 tablets 4 mg (400 mg total)
• Manufactured in: Switzerland

Product Overview

Salbutamol (USAN: albuterol) is a short-acting, selective 2-adrenergic receptor agonist used

in laboratories as a reference bronchodilator and 2-selectivity probe. It relaxes airway

smooth muscle via 2-receptor activation, cAMP elevation, and PKA-mediated reduction of intracellular calcium.

Because of its well-defined pharmacology, salbutamol is a core comparator in respiratory and receptor-target

studies.

Key Research Highlights

2-agonist benchmark:

Canonical reference for bronchodilation, cAMP signaling, 2-selectivity, and smooth-muscle physiology studies.

Exercise physiology & anti-doping relevance:

Controlled studies show no performance improvement in non-asthmatic athletes at inhaled doses up to

1600 g/24 h (JSSM). Used extensively in anti-doping pharmacokinetics research.

WADA compliance modeling:

WADA permits only inhaled salbutamol 1600 g/24 h; oral/systemic administration is prohibited.

Urinary threshold: ~1000 ng/mL (S3 Beta-2 Agonists).

Suggested Laboratory Applications

• 2-receptor pharmacology assays
• Bronchodilator response and smooth-muscle relaxation studies
• cAMP/PKA signaling models
• Receptor selectivity and structure-activity analyses
• Anti-doping threshold and detection research

Technical Specifications

Storage

Store dry, cool, and protected from light; follow SDS

Shelf-Life

36 months (per COA/label)

Mechanism of Action (Laboratory Context)

Activation of 2-receptors (Gs-coupled) stimulation of adenylyl cyclase

cAMP PKA activation reduced intracellular Ca2+ & MLCK activity smooth-muscle relaxation

and bronchodilation.

Documented Research Side Effects

• Tremor and fine-muscle activation
• Tachycardia and palpitations (1 spillover at higher doses)
• Hypokalemia via 2-mediated potassium shift
• Lactic acidosis in high systemic exposures
• Hyperglycemia and metabolic shifts
• Rare hypersensitivity reactions reported in clinical labeling

Handling & Compliance

For Research Use Only — not a medicine, supplement, or veterinary product.

Buyer affirms qualified laboratory use and compliance with institutional SOPs and local regulations.

Salbutamol is regulated under WADA S3 Beta-2 Agonists; systemic/oral use is prohibited without a TUE.